Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7664384 | 0.86 | CHRNB2 (0.42) | CHRNB2CHRNA4SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7667761 | 0.81 | ALDH1A1 (0.52) | CHRNB2CHRNA4SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7667758 | 0.81 | ALDH1A1 (0.52) | CHRNB2CHRNA4SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7654949 | 0.79 | CHRNA1 (0.54) | CHRNB2CHRNA4SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7658602 | 0.74 | MEN1 (0.43) | CHRNB2CHRNA4SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7659233 | 0.74 | CHRNA7 (0.60) | CHRNB2CHRNA4SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7665043 | 0.73 | SMN1; SMN2 (0.50) | CHRNB2CHRNA4SMN1; SMN2CHRNA1CHRNA7 | |
| SCHEMBL7665049 | 0.73 | SMN1; SMN2 (0.50) | CHRNB2CHRNA4SMN1; SMN2CHRNA1CHRNA7 | |
| SCHEMBL7665999 | 0.71 | CHRNA1 (0.53) | CHRNB2CHRNA4SMN1; SMN2CHRNA1CHRNA7 | |
| SCHEMBL7665988 | 0.66 | ALDH1A1 (0.52) | CHRNB2CHRNA4SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6465492-B1 | SUCH AS 2-((4-METHYLPHENYL)SULFONYLIMINO) IMIDAZOLIDINE; PESTICIDES; KILLING INSECTS ON PLANTS | SINON CORPORATION (TW) | 2002-10-15 | — | — | US | disclosed |