SCHEMBL7667758

SCHEMBL7667758

O=S(=O)(/N=C1/NCCN1Cc1ccc(Cl)nc1)c1ccc(Cl)cc1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
CHRNA1 P02708 3/20 0.47
CHRNA7 P36544 3/20 0.47
CHRNA3 P32297 2/20 0.47
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
CHRNB2 P17787 1/20 0.43
CHRNA4 P43681 1/20 0.43
PSEN1 P49768 1/20 0.42
PSEN2 P49810 1/20 0.42
APH1B Q8WW43 1/20 0.42
NCSTN Q92542 1/20 0.42
APH1A Q96BI3 1/20 0.42
PSENEN Q9NZ42 1/20 0.42
NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7667761 1.00 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2CHRNA1CHRNA7CHRNA3
SCHEMBL7654949 0.95 CHRNA1 (0.54) ALDH1A1SMN1; SMN2CHRNA1CHRNA7CHRNA3
SCHEMBL7665043 0.91 SMN1; SMN2 (0.50) ALDH1A1SMN1; SMN2CHRNA1CHRNA7CHRNA3
SCHEMBL7665049 0.91 SMN1; SMN2 (0.50) ALDH1A1SMN1; SMN2CHRNA1CHRNA7CHRNA3
SCHEMBL7665999 0.86 CHRNA1 (0.53) ALDH1A1SMN1; SMN2CHRNA1CHRNA7CHRNA3
SCHEMBL7665988 0.85 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2CHRNA1CHRNA7CHRNA3
SCHEMBL7654952 0.81 CHRNB2 (0.42) ALDH1A1SMN1; SMN2CHRNA1CHRNA7CHRNA3
SCHEMBL7664381 0.80 CHRNA1 (0.54) ALDH1A1SMN1; SMN2CHRNA1CHRNA7CHRNA3
SCHEMBL7659233 0.79 CHRNA7 (0.60) ALDH1A1SMN1; SMN2CHRNA1CHRNA7CHRNA3
SCHEMBL7658602 0.79 MEN1 (0.43) ALDH1A1SMN1; SMN2CHRNA1CHRNA7CHRNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6465492-B1 SUCH AS 2-((4-METHYLPHENYL)SULFONYLIMINO) IMIDAZOLIDINE; PESTICIDES; KILLING INSECTS ON PLANTS SINON CORPORATION (TW) 2002-10-15 US disclosed