Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SPR | P35270 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7661047 | 0.88 | RAB9A (0.54) | LMNANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL7669102 | 0.78 | CRHBP (0.43) | LMNANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL7660400 | 0.76 | RAB9A (0.52) | LMNANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL5863762 | 0.68 | NPC1 (0.61) | LMNANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL27506182 | 0.66 | NPC1 (0.58) | LMNANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL10489681 | 0.66 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL12552814 | 0.65 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2MAPTMAOB | |
| SCHEMBL20389370 | 0.65 | NAMPT (0.76) | LMNANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL10489837 | 0.65 | NPC1 (0.76) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL9588889 | 0.64 | NPC1 (0.70) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472537-B1 | POLYMERS FROM PRIMARY AMINE AND CARBOXYLIC ACID SUBSTITUTED PYROLE, HYDROXYPYROLE AND IMIDAZOLE MONOMERS AND HAVING 4-AMINOBUTYRIC ACID LINKER FORMING HAIRPIN TURNS AND OPTION-ALLY AMINO ACID RESIDUES; BINDING TO SPECIFIC | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2002-10-29 | — | — | US | disclosed |