Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7660400 | 0.89 | RAB9A (0.52) | NPC1RAB9AMAPTALDH1A1GAA | |
| SCHEMBL7661047 | 0.87 | RAB9A (0.54) | CRHBPCRHR2NPC1RAB9AMAPT | |
| SCHEMBL6835329 | 0.85 | MKNK2 (0.41) | CRHBPCRHR2NPC1RAB9AMAPT | |
| SCHEMBL6831525 | 0.83 | ALDH1A1 (0.42) | CRHBPCRHR2MAPTALDH1A1GAA | |
| SCHEMBL7655751 | 0.78 | LMNA (0.44) | CRHBPCRHR2NPC1RAB9AMAPT | |
| SCHEMBL6835125 | 0.75 | MKNK2 (0.36) | CRHBPCRHR2NPC1RAB9AMAPT | |
| SCHEMBL8192539 | 0.74 | NPC1 (0.43) | CRHBPCRHR2NPC1RAB9ASYK | |
| SCHEMBL6834321 | 0.73 | CNR2 (0.38) | MAPTALDH1A1GAALMNACNR2 | |
| SCHEMBL3556821 | 0.71 | MEN1 (0.41) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL12872990 | 0.70 | ALDH1A1 (0.56) | NPC1RAB9ASYKMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472537-B1 | POLYMERS FROM PRIMARY AMINE AND CARBOXYLIC ACID SUBSTITUTED PYROLE, HYDROXYPYROLE AND IMIDAZOLE MONOMERS AND HAVING 4-AMINOBUTYRIC ACID LINKER FORMING HAIRPIN TURNS AND OPTION-ALLY AMINO ACID RESIDUES; BINDING TO SPECIFIC | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2002-10-29 | — | — | US | disclosed |