Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 1/20 | 0.56 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | GPR183 | P32249 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656013 | 1.00 | YAP1 (0.56) | YAP1TEAD4ALDH1A1HTTGPR183 | |
| SCHEMBL7654785 | 0.83 | YAP1 (0.61) | YAP1TEAD4ALDH1A1HTTGPR183 | |
| SCHEMBL7076859 | 0.83 | YAP1 (0.61) | YAP1TEAD4ALDH1A1HTTGPR183 | |
| SCHEMBL7071884 | 0.81 | ALDH1A1 (0.68) | YAP1TEAD4ALDH1A1HTTGPR183 | |
| SCHEMBL7071881 | 0.81 | ALDH1A1 (0.68) | YAP1TEAD4ALDH1A1HTTGPR183 | |
| SCHEMBL7649426 | 0.80 | ALDH1A1 (0.51) | ALDH1A1GAALMNASMN1; SMN2KMT2A | |
| Acetic Acid SCHEMBL27525184 | 0.79 | ALDH1A1 (0.64) | YAP1TEAD4ALDH1A1HTTGPR183 | |
| SCHEMBL7650417 | 0.77 | PKM (0.61) | ALDH1A1HTTGAALMNASMN1; SMN2 | |
| SCHEMBL7649428 | 0.77 | ALDH1A1 (0.53) | YAP1TEAD4ALDH1A1HTTGPR183 | |
| SCHEMBL7649424 | 0.77 | ALDH1A1 (0.53) | YAP1TEAD4ALDH1A1HTTGPR183 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |