Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 18/20 | 0.47 |
| ▸ | CTSL | P07711 | 8/20 | 0.47 |
| ▸ | CTSK | P43235 | 7/20 | 0.47 |
| ▸ | CTSB | P07858 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6744961 | 0.85 | CTSS (0.48) | CTSSCTSLCTSKCTSB | |
| SCHEMBL6063314 | 0.84 | CTSS (0.40) | CTSSCTSLCTSKCTSB | |
| SCHEMBL7656057 | 0.84 | CTSS (0.40) | CTSSCTSLCTSKCTSB | |
| SCHEMBL6629207 | 0.82 | CTSS (0.45) | CTSSCTSLCTSKCTSB | |
| SCHEMBL7656003 | 0.81 | CTSS (0.55) | CTSSCTSLCTSKCTSB | |
| SCHEMBL7655999 | 0.81 | CTSS (0.55) | CTSSCTSLCTSKCTSB | |
| SCHEMBL5955838 | 0.77 | CTSS (0.60) | CTSSCTSLCTSKCTSB | |
| SCHEMBL6628713 | 0.77 | CTSS (0.47) | CTSSCTSLCTSKCTSB | |
| SCHEMBL6628710 | 0.77 | CTSS (0.47) | CTSSCTSLCTSKCTSB | |
| SCHEMBL6740690 | 0.75 | CTSS (0.45) | CTSSCTSLCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492362-B1 | Compounds and compositions as cathepsin S inhibitors | AXYS PHARMACEUTICALS, INC. | 2002-12-10 | — | — | US | disclosed |