Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | RXRB | P28702 | 2/20 | 0.36 |
| ▸ | RXRG | P48443 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPD | P32754 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7651791 | 0.87 | MAPT (0.40) | MAPTRAB9AALDH1A1LMNAKMT2A | |
| SCHEMBL7649126 | 0.82 | KMT2A (0.51) | MAPTRAB9AALDH1A1LMNAKMT2A | |
| SCHEMBL7997909 | 0.77 | LMNA (0.49) | MAPTRAB9AALDH1A1LMNAKMT2A | |
| SCHEMBL7795079 | 0.76 | MEN1 (0.40) | MAPTRAB9AKMT2APTPN1PTPN6 | |
| SCHEMBL7652479 | 0.76 | MAPT (0.43) | MAPTRAB9AALDH1A1LMNAKMT2A | |
| SCHEMBL7800206 | 0.74 | LMNA (0.45) | MAPTRAB9AALDH1A1LMNAKMT2A | |
| SCHEMBL7652342 | 0.71 | KMT2A (0.56) | MAPTRAB9AALDH1A1LMNAKMT2A | |
| SCHEMBL7657358 | 0.70 | KMT2A (0.42) | MAPTRAB9AALDH1A1LMNAKMT2A | |
| SCHEMBL7654964 | 0.69 | MAPT (0.49) | MAPTRAB9AALDH1A1LMNAKMT2A | |
| SCHEMBL2991148 | 0.69 | HTT (0.53) | RAB9AALDH1A1KMT2ATDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6437178-B2 | REACTING A HALOGENATED BENZENE COMPOUND WITH NITRO(THIO)PHENOL; REDUCTION | INFINEON TECHNOLOGIES AG (DE) | 2002-08-20 | — | — | US | disclosed |