Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 3/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.35 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7663246 | 0.83 | MRGPRX4 (0.48) | MRGPRX4PLAU | |
| SCHEMBL3415738 | 0.80 | CHRM3 (0.51) | CTSSCTSBCTSKCHRM3BRD4 | |
| SCHEMBL21711969 | 0.79 | HDAC1 (0.45) | CTSSCTSBCTSKCHRM3BRD4 | |
| SCHEMBL352314 | 0.78 | ERCC1 (0.52) | CTSSCTSBCTSKBRD4CREBBP | |
| SCHEMBL7668689 | 0.78 | PLAU (0.43) | MRGPRX4CTSSCTSKPLAUEGLN1 | |
| SCHEMBL7668685 | 0.77 | MRGPRX4 (0.45) | MRGPRX4PLAU | |
| SCHEMBL7670999 | 0.77 | MRGPRX4 (0.46) | MRGPRX4CHRM3PLAUEGLN1 | |
| SCHEMBL7038825 | 0.76 | NOTCH1 (0.44) | — | |
| SCHEMBL7660510 | 0.76 | NR1H2 (0.45) | EGLN1PDCD1CD274 | |
| SCHEMBL6748324 | 0.76 | HRH2 (0.49) | CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348478-B1 | BLOOD COAGULATION FACTORS AND ANTICOAGULANTS | TEIJIN LIMITED (JP) | 2002-02-19 | — | — | US | disclosed |
| EP-1043311-A1 | BIPHENYLAMIDINE DERIVATIVES | TEIJIN LIMITED (JP) | 2000-10-11 | — | — | EP | disclosed |