Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 3/20 | 0.49 |
| ▸ | HRH1 | P35367 | 3/20 | 0.49 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7038825 | 0.86 | NOTCH1 (0.44) | CETPCCR5PKMSLC2A1 | |
| SCHEMBL6748325 | 0.81 | CHRM3 (0.38) | HRH2HRH1MCHR1CCR5SLC2A1 | |
| SCHEMBL6318034 | 0.80 | KDM4E (0.46) | CETPPKM | |
| SCHEMBL6751488 | 0.78 | CCR5 (0.44) | MCHR1CETPCCR5HRH3 | |
| SCHEMBL7661439 | 0.78 | NAMPT (0.43) | HRH2HRH1 | |
| SCHEMBL1632572 | 0.78 | FAAH (0.53) | HRH2HRH1MCHR1HTR1ADRD2 | |
| SCHEMBL6812071 | 0.78 | GPR119 (0.42) | MCHR1CETPHRH3PKMSLC2A1 | |
| SCHEMBL6750024 | 0.78 | NOTCH1 (0.44) | CETPCCR5PKM | |
| SCHEMBL27459780 | 0.78 | MGLL (0.44) | CETPCCR5PKM | |
| SCHEMBL6749986 | 0.77 | GPR119 (0.43) | MCHR1HRH3PKMSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043310-B1 | BIPHENYLAMIDINE DERIVATIVES | TEIJIN LTD (JP) | 2004-06-09 | — | — | EP | disclosed |
| US-6706745-B1 | THERAPY FOR ANTICOAGULATION PLAYS AN IMPORTANT PART IN THE MEDICAL TREATMENT AND PROPHYLAXIS OF THROMBOEMBOLISMS | TEIJIN LIMITED (JP) | 2004-03-16 | — | — | US | disclosed |