Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.48 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7668689 | 0.89 | PLAU (0.43) | MRGPRX4KAT6APLAU | |
| SCHEMBL7662548 | 0.89 | MRGPRX4 (0.51) | MRGPRX4KAT6APLAULMNAHPGD | |
| SCHEMBL7668685 | 0.89 | MRGPRX4 (0.45) | MRGPRX4KAT6APLAU | |
| SCHEMBL6751413 | 0.85 | PLAU (0.47) | MRGPRX4KAT6APLAULOXL2XDH | |
| SCHEMBL7714047 | 0.84 | MRGPRX4 (0.51) | MRGPRX4KAT6APLAUGABRG2GABRB3 | |
| SCHEMBL6749963 | 0.84 | CYP4F2 (0.48) | MRGPRX4KAT6APLAULOXL2XDH | |
| SCHEMBL6753784 | 0.84 | LOXL2 (0.53) | MRGPRX4KAT6APLAULOXL2XDH | |
| SCHEMBL7656178 | 0.83 | MRGPRX4 (0.42) | MRGPRX4PLAU | |
| SCHEMBL6751721 | 0.83 | PLAU (0.41) | MRGPRX4KAT6APLAU | |
| SCHEMBL7665912 | 0.82 | MRGPRX4 (0.48) | MRGPRX4PLAULMNAGPR34 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348478-B1 | BLOOD COAGULATION FACTORS AND ANTICOAGULANTS | TEIJIN LIMITED (JP) | 2002-02-19 | — | — | US | disclosed |
| EP-1043311-A1 | BIPHENYLAMIDINE DERIVATIVES | TEIJIN LIMITED (JP) | 2000-10-11 | — | — | EP | disclosed |