Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7658946 | 0.90 | MRGPRX4 (0.51) | MRGPRX4PLAUMMP13 | |
| SCHEMBL7663246 | 0.89 | MRGPRX4 (0.48) | MRGPRX4PLAUKAT6A | |
| SCHEMBL7668689 | 0.87 | PLAU (0.43) | MRGPRX4PLAUMMP12MMP13KAT6A | |
| SCHEMBL7662094 | 0.83 | F10 (0.46) | — | |
| SCHEMBL6751413 | 0.81 | PLAU (0.47) | MRGPRX4PLAUMMP12MMP13KAT6A | |
| SCHEMBL7662548 | 0.80 | MRGPRX4 (0.51) | MRGPRX4PLAUKAT6A | |
| SCHEMBL7714047 | 0.80 | MRGPRX4 (0.51) | MRGPRX4PLAUKAT6A | |
| SCHEMBL6753784 | 0.80 | LOXL2 (0.53) | MRGPRX4PLAUMMP12MMP13KAT6A | |
| SCHEMBL6749963 | 0.80 | CYP4F2 (0.48) | MRGPRX4PLAUMMP12MMP13KAT6A | |
| SCHEMBL7041658 | 0.79 | CCR5 (0.44) | MRGPRX4PLAUMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348478-B1 | BLOOD COAGULATION FACTORS AND ANTICOAGULANTS | TEIJIN LIMITED (JP) | 2002-02-19 | — | — | US | disclosed |
| EP-1043311-A1 | BIPHENYLAMIDINE DERIVATIVES | TEIJIN LIMITED (JP) | 2000-10-11 | — | — | EP | disclosed |