Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 14/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656290 | 0.95 | ADAM17 (0.58) | ADAM17 | |
| SCHEMBL7656200 | 0.89 | ADAM17 (0.51) | ADAM17 | |
| Trifluoroacetic Acid SCHEMBL6736529 | 0.85 | ADAM17 (0.62) | ADAM17 | |
| Trifluoroacetic Acid SCHEMBL6741899 | 0.83 | ADAM17 (0.57) | ADAM17 | |
| Trifluoroacetic Acid SCHEMBL6744361 | 0.83 | ADAM17 (0.62) | ADAM17 | |
| Trifluoroacetic Acid SCHEMBL6742567 | 0.83 | ADAM17 (0.62) | ADAM17 | |
| SCHEMBL6741074 | 0.80 | ADAM17 (0.68) | ADAM17 | |
| Trifluoroacetic Acid SCHEMBL6736943 | 0.80 | ADAM17 (0.57) | ADAM17 | |
| Trifluoroacetic Acid SCHEMBL6736923 | 0.79 | ADAM17 (0.57) | ADAM17 | |
| SCHEMBL6736532 | 0.78 | ADAM17 (0.53) | ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376665-B1 | ANTIARTHRITIC AGENTS, ANTIINFLAMMATORY AGENTS | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-04-23 | — | — | US | disclosed |