Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 14/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7656192 | 0.89 | ADAM17 (0.55) | ADAM17 | |
| SCHEMBL7656290 | 0.88 | ADAM17 (0.58) | ADAM17 | |
| SCHEMBL6736532 | 0.86 | ADAM17 (0.53) | ADAM17MMP3 | |
| SCHEMBL6741903 | 0.83 | ADAM17 (0.49) | ADAM17MMP3 | |
| SCHEMBL6744364 | 0.83 | ADAM17 (0.54) | ADAM17MMP3 | |
| SCHEMBL6742570 | 0.83 | ADAM17 (0.54) | ADAM17MMP3 | |
| Trifluoroacetic Acid SCHEMBL6736529 | 0.78 | ADAM17 (0.62) | ADAM17 | |
| SCHEMBL6737327 | 0.78 | ADAM17 (0.49) | ADAM17MMP3 | |
| SCHEMBL6835118 | 0.77 | ADAM17 (0.53) | ADAM17MMP2MMP9 | |
| SCHEMBL6737356 | 0.76 | ADAM17 (0.47) | ADAM17MMP2MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376665-B1 | ANTIARTHRITIC AGENTS, ANTIINFLAMMATORY AGENTS | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-04-23 | — | — | US | disclosed |