Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.41 |
| ▸ | MAPT | P10636 | 9/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | POLR1A | O95602 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7660385 | 0.99 | OGA (0.42) | OGAALDH1A1MAPTHPGDLMNA | |
| SCHEMBL7663203 | 0.90 | OGA (0.43) | OGAALDH1A1MAPTHPGDLMNA | |
| SCHEMBL7661575 | 0.90 | PIK3CB (0.43) | OGAALDH1A1MAPTHPGDLMNA | |
| SCHEMBL7655787 | 0.81 | OGA (0.44) | OGAALDH1A1MAPTHPGDLMNA | |
| SCHEMBL7658990 | 0.80 | OGA (0.45) | OGAALDH1A1MAPTHPGDLMNA | |
| SCHEMBL8211686 | 0.75 | HPGD (0.45) | ALDH1A1MAPTHPGDSMN1; SMN2ALOX15 | |
| SCHEMBL7657251 | 0.71 | L3MBTL1 (0.44) | OGAALDH1A1MAPTHPGDLMNA | |
| SCHEMBL7653917 | 0.71 | OGA (0.46) | OGAALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL18520607 | 0.65 | ROCK2 (0.39) | ALDH1A1MAPTHPGDLMNASMN1; SMN2 | |
| SCHEMBL18520606 | 0.64 | HPGD (0.39) | ALDH1A1HPGDLMNASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340704-B1 | TREATING NERVE DISEASE OR BONE/JOINT DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |