Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7661575 | 0.86 | PIK3CB (0.43) | HPGDNPC1RAB9AALDH1A1GAA | |
| SCHEMBL7657251 | 0.83 | L3MBTL1 (0.44) | HPGDALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL5241851 | 0.79 | NCF1 (0.64) | HPGDNPC1RAB9AALDH1A1GAA | |
| SCHEMBL7660385 | 0.76 | OGA (0.42) | HPGDNPC1RAB9AALDH1A1GAA | |
| SCHEMBL7656216 | 0.75 | OGA (0.42) | HPGDNPC1RAB9AALDH1A1GAA | |
| SCHEMBL7663203 | 0.74 | OGA (0.43) | HPGDNPC1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL7658990 | 0.73 | OGA (0.45) | HPGDNPC1RAB9AALDH1A1GAA | |
| SCHEMBL7655787 | 0.72 | OGA (0.44) | HPGDNPC1RAB9AALDH1A1GAA | |
| SCHEMBL7653917 | 0.71 | OGA (0.46) | HPGDALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6599066 | 0.70 | PIK3CA (0.52) | GAAPKMNCF1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975621-A1 | CELL DIFFERENTIATION INDUCING AMIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998049155-A1 | CELL DIFFERENTIATION INDUCING AMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-05 | — | — | WO | disclosed |