Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7660195 | 0.91 | HRH3 (0.47) | HRH3KDM4EMEN1ALDH1A1GFER | |
| SCHEMBL7657972 | 0.86 | HRH3 (0.42) | HRH3 | |
| SCHEMBL7655220 | 0.84 | HRH3 (0.39) | HRH3 | |
| SCHEMBL7655188 | 0.84 | HRH3 (0.42) | HRH3 | |
| SCHEMBL7659427 | 0.81 | HRH3 (0.67) | HRH3 | |
| SCHEMBL7664998 | 0.79 | HRH3 (0.50) | HRH3KDM4EMEN1ALDH1A1GFER | |
| SCHEMBL10107170 | 0.78 | HRH3 (0.39) | HRH3 | |
| SCHEMBL10122903 | 0.77 | HRH3 (0.43) | HRH3KDM4EMEN1ALDH1A1GFER | |
| SCHEMBL7656388 | 0.77 | HRH3 (0.65) | HRH3 | |
| SCHEMBL7659514 | 0.75 | RAPGEF3 (0.46) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002085861-A1 | IMIDAZOLIDINE COMPOUNDS AND THEIR USE AS CXCR3 ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-10-31 | — | — | WO | disclosed |
| US-6469002-B1 | COMPOUNDS WHICH MODULATE CHEMOKINE RECEPTOR ACTIVITY AND ARE USEFUL IN TREATMENT OF INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. | 2002-10-22 | — | — | US | disclosed |