Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 5/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12239032 | 0.82 | ST14 (0.46) | ST14MAOBFFAR1MAPTAR | |
| SCHEMBL756590 | 0.82 | L3MBTL1 (0.48) | ST14MAOBL3MBTL1MAPTRAB9A | |
| SCHEMBL12239027 | 0.82 | ST14 (0.46) | ST14MAOBNR3C1L3MBTL1LMNA | |
| SCHEMBL10121117 | 0.79 | L3MBTL1 (0.51) | ST14MAOBL3MBTL1LMNAMAPT | |
| SCHEMBL12238995 | 0.79 | LOXL2 (0.46) | ST14MAOBLOXLOXL2 | |
| SCHEMBL923193 | 0.78 | MAOB (0.57) | ST14MAOBFFAR1NR3C1LOX | |
| SCHEMBL13904294 | 0.77 | ST14 (0.50) | ST14MAOBFFAR1 | |
| SCHEMBL12239033 | 0.77 | SCN9A (0.42) | ST14MAOBFFAR1ARSCN9A | |
| Trifluoroacetic Acid SCHEMBL2545491 | 0.75 | NR3C1 (0.43) | ST14MAOBFFAR1NR3C1SCN9A | |
| SCHEMBL12239037 | 0.75 | LOXL2 (0.55) | LMNAMAPTLOXL2ARSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188254-B1 | NOVEL BRADYKININ B1-ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2012-03-21 | — | — | EP | disclosed |
| WO-2009027450-A1 | NOVEL BRADYKININ B1-ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-03-05 | — | — | WO | disclosed |