Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6895470 | 0.85 | HDAC3 (0.33) | MC4RHDAC3HDAC8 | |
| SCHEMBL6897620 | 0.85 | SIGMAR1 (0.37) | MC4R | |
| SCHEMBL27559931 | 0.81 | CACNA1B (0.38) | — | |
| SCHEMBL6897654 | 0.75 | MC4R (0.37) | MC4R | |
| SCHEMBL7214805 | 0.74 | TACR1 (0.38) | — | |
| SCHEMBL6894683 | 0.71 | MMP2 (0.39) | — | |
| SCHEMBL6890733 | 0.71 | HSD17B10 (0.47) | — | |
| SCHEMBL7676098 | 0.70 | SIGMAR1 (0.40) | MC4R | |
| SCHEMBL6896883 | 0.70 | SIGMAR1 (0.40) | MC4R | |
| SCHEMBL6740809 | 0.68 | CHRNB2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492370-B1 | Urea derivatives and pharmaceutical compositions thereof | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-12-10 | — | — | US | disclosed |
| EP-1072591-A1 | NOVEL UREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-01-31 | — | — | EP | disclosed |