Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | CFTR | P13569 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705197 | 0.84 | GAA (0.65) | ALDH1A1CFTRHSD17B10GAAABCB1 | |
| SCHEMBL6437163 | 0.84 | SLC6A3 (0.59) | ALDH1A1CFTRHSD17B10GAASLC6A3 | |
| SCHEMBL7656620 | 0.82 | SLC6A3 (0.61) | ALDH1A1CFTRHSD17B10GAASLC6A3 | |
| SCHEMBL2726928 | 0.81 | GAA (0.54) | ALDH1A1CFTRHSD17B10GAAABCB1 | |
| SCHEMBL29706660 | 0.81 | GAA (0.50) | ALDH1A1CFTRHSD17B10GAAABCB1 | |
| SCHEMBL5099640 | 0.81 | GAA (0.50) | ALDH1A1CFTRHSD17B10GAAABCB1 | |
| Dimethyl Phthalate SCHEMBL28028655 | 0.80 | GAA (0.66) | ALDH1A1CFTRHSD17B10GAASLC6A3 | |
| SCHEMBL9648251 | 0.80 | GAA (0.66) | ALDH1A1CFTRHSD17B10GAASLC6A3 | |
| SCHEMBL713768 | 0.80 | KDM4E (0.65) | ALDH1A1HSD17B10GAAUSP2MEN1 | |
| SCHEMBL69464 | 0.80 | SLC6A3 (0.67) | ALDH1A1CFTRHSD17B10SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358960-B1 | FOR THERAPY OF INTRAVASCULAR COAGULATION, CORONARY THROMBOSIS, CEREBRAL INFARCTION, CEREBRAL EMBOLISM, TRANSIENT ISCHEMIC ATTACK, CEREBROVASCULAR DISORDERS, PULMONARY VASCULAR DISEASES, DEEP VENOUS THROMBOSIS, ETC. | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-1078917-A1 | AMIDINO DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-02-28 | — | — | EP | disclosed |