Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.46 |
| ▸ | PGR | P06401 | 4/20 | 0.44 |
| ▸ | RORA | P35398 | 2/20 | 0.44 |
| ▸ | RORC | P51449 | 2/20 | 0.44 |
| ▸ | RORB | Q92753 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7649604 | 0.96 | CNR2 (0.47) | CNR2PGRRORARORCRORB | |
| SCHEMBL7649524 | 0.82 | TSHR (0.56) | CNR2PGRRORARORCRORB | |
| SCHEMBL7649598 | 0.78 | TSHR (0.55) | CNR2PGRRORARORCRORB | |
| SCHEMBL22716908 | 0.77 | MPO (0.46) | CNR2PGRKDM4EALDH1A1LMNA | |
| SCHEMBL31189225 | 0.77 | MPO (0.46) | CNR2PGRKDM4EALDH1A1LMNA | |
| SCHEMBL4547798 | 0.75 | ERCC1 (0.44) | CNR2PGRKDM4EALDH1A1LMNA | |
| SCHEMBL22745921 | 0.74 | P2RX4 (0.64) | PGRKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL541993 | 0.73 | FABP4 (0.56) | CNR2 | |
| SCHEMBL2700703 | 0.73 | FABP4 (0.56) | CNR2 | |
| SCHEMBL7649581 | 0.73 | CNR2 (0.56) | CNR2KDM4EMAPTSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407116-B1 | 2,4-DIOXO-1,2,3,4-TETRAHYDROQUINAZOLINE DERIVATIVES; ANTIALLERGENS, ANTIASTHMATICS, ANTIHISTAMINES, AND ANTIINFLAMMATORY AGENTS | TAKEDA CHEMICAL INDUSTRIES, INC. (JP) | 2002-06-18 | — | — | US | disclosed |
| EP-1026160-A1 | NITROGENOUS FUSED-RING COMPOUNDS, PROCESS FOR THE PREPARATION OF THE SAME, AND DRUGS | Takeda Chemical Industries, Ltd. (JP) | 2000-08-09 | — | — | EP | disclosed |