Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6206600 | 0.82 | ABCG2 (0.44) | LMNAHPGDPKMMAPK14KDM4C | |
| SCHEMBL6996541 | 0.78 | ALDH1A1 (0.44) | MAPTLMNAHPGDMEN1NPC1 | |
| SCHEMBL339590 | 0.76 | SMN1; SMN2 (0.41) | LMNAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL29625406 | 0.76 | PARP1 (0.54) | LMNAHPGDNPC1RAB9ACHEK1 | |
| SCHEMBL1720148 | 0.76 | PARP1 (0.54) | LMNAHPGDNPC1RAB9ACHEK1 | |
| SCHEMBL29514911 | 0.75 | AKR1C3 (0.47) | MAPTNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL7002428 | 0.75 | AKR1C3 (0.47) | MAPTNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL340702 | 0.74 | KDM4C (0.52) | LMNAHPGDKDM4CGSK3BMAOB | |
| SCHEMBL29442138 | 0.74 | KDM4C (0.52) | LMNAHPGDKDM4CGSK3BMAOB | |
| SCHEMBL7851584 | 0.73 | KDM4E (0.42) | MAPTLMNAHPGDMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340704-B1 | TREATING NERVE DISEASE OR BONE/JOINT DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |