Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7662241 | 0.82 | HRH3 (0.42) | HRH3 | |
| SCHEMBL6739645 | 0.79 | HRH3 (0.40) | HRH3 | |
| SCHEMBL6735212 | 0.79 | KAT2B (0.38) | HRH3 | |
| SCHEMBL7654001 | 0.74 | HRH3 (0.64) | HRH3 | |
| SCHEMBL7665084 | 0.73 | HRH3 (0.34) | HRH3 | |
| SCHEMBL7656218 | 0.70 | HRH3 (0.47) | HRH3 | |
| SCHEMBL6734463 | 0.68 | ACKR3 (0.44) | — | |
| SCHEMBL7655220 | 0.68 | HRH3 (0.39) | HRH3 | |
| SCHEMBL7657968 | 0.67 | KMT2A (0.32) | — | |
| SCHEMBL6733915 | 0.64 | HRH3 (0.40) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002085861-A1 | IMIDAZOLIDINE COMPOUNDS AND THEIR USE AS CXCR3 ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-10-31 | — | — | WO | disclosed |
| US-6469002-B1 | COMPOUNDS WHICH MODULATE CHEMOKINE RECEPTOR ACTIVITY AND ARE USEFUL IN TREATMENT OF INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. | 2002-10-22 | — | — | US | disclosed |