Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9219515 | 0.79 | SCN9A (0.32) | KMT2ARAB9A | |
| SCHEMBL4387644 | 0.78 | HRH3 (0.34) | ALDH1A1 | |
| SCHEMBL7656144 | 0.76 | HRH3 (0.33) | ALDH1A1 | |
| SCHEMBL9215512 | 0.76 | LMNA (0.32) | RAB9AALDH1A1 | |
| SCHEMBL9852543 | 0.75 | SCN9A (0.30) | — | |
| SCHEMBL4394520 | 0.75 | HRH3 (0.37) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL9219620 | 0.75 | ACHE (0.34) | — | |
| SCHEMBL9216873 | 0.75 | CHRM2 (0.41) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL6284635 | 0.73 | KMT2A (0.49) | KMT2ARAB9AMEN1ALDH1A1 | |
| SCHEMBL9217125 | 0.72 | ACHE (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002085861-A1 | IMIDAZOLIDINE COMPOUNDS AND THEIR USE AS CXCR3 ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-10-31 | — | — | WO | disclosed |
| US-6469002-B1 | COMPOUNDS WHICH MODULATE CHEMOKINE RECEPTOR ACTIVITY AND ARE USEFUL IN TREATMENT OF INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. | 2002-10-22 | — | — | US | disclosed |