Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | OGA | O60502 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7658990 | 0.80 | OGA (0.45) | HPGDALDH1A1KDM4EATMSMN1; SMN2 | |
| SCHEMBL7655787 | 0.79 | OGA (0.44) | HPGDALDH1A1KDM4EATMSMN1; SMN2 | |
| SCHEMBL7653917 | 0.78 | OGA (0.46) | HPGDALDH1A1KDM4EATMSMN1; SMN2 | |
| SCHEMBL7657251 | 0.78 | L3MBTL1 (0.44) | HPGDALDH1A1KDM4EATMSMN1; SMN2 | |
| SCHEMBL9319008 | 0.78 | TNF (0.50) | HPGDALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL9729781 | 0.76 | ALDH1A1 (0.55) | HPGDALDH1A1KDM4EATMSMN1; SMN2 | |
| SCHEMBL23198681 | 0.75 | ALDH1A1 (0.45) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPT | |
| SCHEMBL17540948 | 0.75 | ALDH1A1 (0.45) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPT | |
| SCHEMBL163381 | 0.75 | SMN1; SMN2 (0.53) | ALDH1A1KDM4ESMN1; SMN2LMNATDP1 | |
| SCHEMBL5929729 | 0.74 | ALDH1A1 (0.52) | HPGDALDH1A1KDM4ESMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340704-B1 | TREATING NERVE DISEASE OR BONE/JOINT DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0975621-A1 | CELL DIFFERENTIATION INDUCING AMIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998049155-A1 | CELL DIFFERENTIATION INDUCING AMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-05 | — | — | WO | disclosed |