Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 9/20 | 0.55 |
| ▸ | PYGM | P11217 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7126670 | 0.81 | PYGL (0.63) | PYGLPYGMALDH1A1MAPTMEN1 | |
| SCHEMBL4092971 | 0.76 | KMT2A (0.71) | PYGLPYGMALDH1A1MAPTMEN1 | |
| SCHEMBL2271993 | 0.75 | ALDH1A1 (0.61) | PYGLPYGMALDH1A1MAPTMEN1 | |
| SCHEMBL7116140 | 0.75 | PYGL (0.66) | PYGLPYGMALDH1A1MAPTMEN1 | |
| SCHEMBL7118351 | 0.74 | PYGL (0.54) | PYGLPYGMALDH1A1MAPTMEN1 | |
| SCHEMBL4950322 | 0.73 | AKR1C4 (0.69) | PYGLPYGMALDH1A1MAPTMEN1 | |
| SCHEMBL29472407 | 0.73 | AKR1C4 (0.69) | PYGLPYGMALDH1A1MAPTMEN1 | |
| SCHEMBL30249770 | 0.73 | PYGL (0.73) | PYGLPYGMALDH1A1MAPTMEN1 | |
| SCHEMBL7126045 | 0.73 | PYGL (0.73) | PYGLPYGMALDH1A1MAPTMEN1 | |
| SCHEMBL14075256 | 0.73 | KMT2A (0.62) | PYGLPYGMALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1220832-A1 | NOVEL AROMATIC COMPOUNDS | NOVO NORDISK A/S (DK) | 2002-07-10 | — | — | EP | disclosed |
| WO-2001023347-A1 | NOVEL AROMATIC COMPOUNDS | NOVO NORDISK A/S (DK) | 2001-04-05 | — | — | WO | disclosed |