Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.71 |
| ▸ | MEN1 | O00255 | 6/20 | 0.71 |
| ▸ | PKM | P14618 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.69 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.69 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.69 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | PYGL | P06737 | 2/20 | 0.67 |
| ▸ | PYGM | P11217 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7116140 | 0.88 | PYGL (0.66) | KMT2AMEN1PKMALDH1A1MAPT | |
| SCHEMBL882472 | 0.88 | RAB9A (0.67) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2273640 | 0.86 | HDAC2 (0.67) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL4094329 | 0.86 | KMT2A (0.66) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2024935 | 0.85 | MEN1 (0.71) | KMT2AMEN1PKMALDH1A1MAPT | |
| SCHEMBL6352508 | 0.85 | AKR1C2 (0.70) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1309081 | 0.85 | SMN1; SMN2 (0.70) | KMT2AMEN1PKMALDH1A1MAPT | |
| SCHEMBL17109793 | 0.84 | ALDH1A1 (0.88) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7126045 | 0.84 | PYGL (0.73) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30249770 | 0.84 | PYGL (0.73) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105218-A1 | CRTH2 Receptor Ligands For Therapeutic Use | 7TM PHARMA A/S (DK) | 2009-04-23 | — | — | US | disclosed |
| US-20090105218-A1 | CRTH2 Receptor Ligands For Therapeutic Use | 7TM PHARMA A/S (DK) | 2009-04-23 | — | — | US | disclosed |
| US-20090105218-A1 | CRTH2 Receptor Ligands For Therapeutic Use | 7TM PHARMA A/S (DK) | 2009-04-23 | — | — | US | disclosed |
| EP-1758571-A1 | CRTH2 RECEPTOR LIGANDS FOR THERAPEUTIC USE | 7TM Pharma A/S (DK) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005115374-A1 | CRTH2 RECEPTOR LIGANDS FOR THERAPEUTIC USE | 7TM PHARMA A/S (DK) | 2005-12-08 | — | — | WO | disclosed |
| US-RE32087-E | 4H-3,1-Benzoxazine derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1986-02-25 | — | — | US | disclosed |
| EP-0084893-A2 | 4H-3,1-Benzoxazin derivatives, methods for their preparation, and their use for combatting undesirable vegetation | BASF Aktiengesellschaft (DE) | 1983-08-03 | — | — | EP | disclosed |
| US-4315766-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1982-02-16 | — | — | US | disclosed |
| EP-0017931-A2 | 4H-3,1-Benzoxazine derivatives, methods of their preparation and their use in combating undesirable vegetation | BASF Aktiengesellschaft (DE) | 1980-10-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105218-A1 | CRTH2 Receptor Ligands For Therapeutic Use | NR1H2, NR1H3, HRH2 | KMT2A 2570/4885MEN1 2859/4885PKM 4396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.