Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.52 |
| ▸ | BAX | Q07812 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL301726 | 0.87 | LTA4H (0.50) | CA4CA1CA2GLACA9 | |
| SCHEMBL15653550 | 0.84 | LTA4H (0.47) | CA4CA1CA2GLACA9 | |
| Diphenylether SCHEMBL1319200 | 0.76 | LTA4H (0.84) | CA4CA12CA1CA2GLA | |
| Diphenylether SCHEMBL21826729 | 0.76 | LTA4H (0.84) | CA4CA12CA1CA2GLA | |
| Diphenylether SCHEMBL27692212 | 0.76 | LTA4H (0.84) | CA4CA12CA1CA2GLA | |
| Diphenylether SCHEMBL11315604 | 0.76 | LTA4H (0.84) | CA4CA12CA1CA2GLA | |
| SCHEMBL645275 | 0.76 | LTA4H (0.45) | CA4CA1CA2GLACA9 | |
| SCHEMBL8780512 | 0.75 | CA4 (0.42) | CA4GLATDP1LTA4HNR1H2 | |
| Phenol SCHEMBL8825085 | 0.74 | CA12 (1.00) | CA4CA12CA1CA2GLA | |
| Phenol SCHEMBL9470299 | 0.74 | CA12 (1.00) | CA4CA12CA1CA2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244738-A1 | BIOMIMETIC SILICONE ELASTOMERS | Xiomateria Limited (GB) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001034695-A1 | BIOMIMETIC SILICONE ELASTOMERS | XIOMATERIA LIMITED (GB) | 2001-05-17 | — | — | WO | disclosed |