SCHEMBL7657861

SCHEMBL7657861

COc1c(N)c(Cl)cc(F)c1-n1c(=O)cc(C(F)(F)F)n(C)c1=O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.32
BCAT1 P54687 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5391301 0.91 BCAT2 (0.32) BCAT2BCAT1
SCHEMBL6683544 0.89 BCAT2 (0.31) BCAT2BCAT1
SCHEMBL7661919 0.87
SCHEMBL7668209 0.86 BCAT2 (0.32) BCAT2BCAT1
SCHEMBL6970724 0.84 COMT (0.30)
SCHEMBL5393287 0.82 L3MBTL1 (0.30)
SCHEMBL6792340 0.81 COMT (0.30)
SCHEMBL5394466 0.81
SCHEMBL7559209 0.81 GRIN2D (0.38)
SCHEMBL5386147 0.80 BCAT2 (0.32) BCAT2BCAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6352958-B1 PRE- AND POST-EMERGENCE HERBICIDES FMC CORPORATION 2002-03-05 US disclosed
US-6077812-A 4-OR 7-(2,6-DI(OXO),3-SUBSTITUTED, 4-TRIFLUOROMETHYL-1,2,3, 6-TETRAHYDROPYRIMIDIN-1-YL)BENZIMIDAZOLES; CONTROLLING WEEDS FMC CORPORATION (US) 2000-06-20 US disclosed
EP-0968207-A1 CYCLOIMIDO-SUBSTITUTED BENZOFUSED HETEROCYCLIC HERBICIDES FMC CORPORATION (US) 2000-01-05 EP disclosed
WO-1998038188-A1 CYCLOIMIDO-SUBSTITUTED BENZOFUSED HETEROCYCLIC HERBICIDES FMC CORPORATION (US) 1998-09-03 WO disclosed
US-5753595-A Herbicidal 3-(substituted benzoxazol-7-yl) and 3-(Substituted benzothiazol-7-yl)-1-substituted-6-trifluoromethyl-2 4-(1h 3h)pyrimidinediones FMC CORPORATION (US) 1998-05-19 US disclosed
WO-1997008170-A1 HERBICIDAL 3-(SUBSTITUTED BENZOXAZOL-7-YL) AND 3-(SUBSTITUTED BENZOTHIAZOL-7-YL)-1-SUBSTITUTED-6-TRIFLUOROMETHYL-2,4-(1H,3H)PYRIMIDINEDIONES FMC CORPORATION (US) 1997-03-06 WO disclosed