Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 6/20 | 0.46 |
| ▸ | FNTB | P49356 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7660347 | 0.92 | FNTA (0.54) | FNTAFNTB | |
| SCHEMBL7656231 | 0.88 | FNTA (0.49) | FNTAFNTBHTTKMT2ACYP3A4 | |
| SCHEMBL7667473 | 0.87 | FNTA (0.54) | FNTAFNTBCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7656299 | 0.86 | FNTA (0.52) | FNTAFNTB | |
| SCHEMBL7657939 | 0.83 | CYP3A4 (0.41) | FNTAFNTBCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7657941 | 0.81 | FNTA (0.37) | FNTAFNTBCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7668699 | 0.81 | FNTA (0.51) | FNTAFNTBPGGT1B | |
| SCHEMBL7660594 | 0.81 | CYP3A4 (0.43) | FNTAFNTBCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7665403 | 0.80 | CYP19A1 (0.41) | PTGS2CYP51A1 | |
| SCHEMBL7654320 | 0.80 | FNTA (0.53) | FNTAFNTBTDP1PGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410539-B1 | ANTICARCINOGENIC AGENTS | ASTRAZENCA UK LIMITED (GB) | 2002-06-25 | — | — | US | claimed |