Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | CYP51A1 | Q16850 | 4/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656582 | 0.84 | CYP51A1 (0.49) | CYP19A1CYP51A1AURKAPDPK1RPS6KB1 | |
| SCHEMBL7660347 | 0.83 | FNTA (0.54) | — | |
| SCHEMBL7657939 | 0.83 | CYP3A4 (0.41) | CYP51A1PTGS2POLB | |
| SCHEMBL7664949 | 0.83 | PTGS2 (0.40) | CYP19A1CYP51A1CYP11B1CYP11B2PTGS2 | |
| SCHEMBL7657941 | 0.81 | FNTA (0.37) | CYP19A1CYP51A1AURKAPDPK1RPS6KB1 | |
| SCHEMBL7657934 | 0.80 | FNTA (0.46) | CYP51A1PTGS2 | |
| SCHEMBL7656299 | 0.78 | FNTA (0.52) | — | |
| SCHEMBL8185720 | 0.78 | CYP24A1 (0.52) | CYP19A1 | |
| SCHEMBL7653706 | 0.76 | PTGS2 (0.47) | CYP51A1PTGS2 | |
| SCHEMBL7667709 | 0.76 | PTGS2 (0.39) | CYP19A1CYP51A1CYP11B1CYP11B2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410539-B1 | ANTICARCINOGENIC AGENTS | ASTRAZENCA UK LIMITED (GB) | 2002-06-25 | — | — | US | disclosed |