Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5847120 | 0.86 | BCAT1 (0.33) | JAK2BTK | |
| SCHEMBL3896362 | 0.85 | JAK2 (0.30) | JAK2BTK | |
| SCHEMBL1400120 | 0.85 | GRM4 (0.32) | — | |
| SCHEMBL7888784 | 0.84 | BCAT2 (0.31) | — | |
| SCHEMBL7881673 | 0.82 | CRHR1 (0.34) | JAK2BTK | |
| SCHEMBL7891247 | 0.82 | — | — | |
| SCHEMBL7950213 | 0.82 | BCAT2 (0.30) | JAK2BTK | |
| SCHEMBL6743751 | 0.81 | BCAT2 (0.38) | — | |
| SCHEMBL7893445 | 0.81 | — | — | |
| SCHEMBL25095853 | 0.81 | BCAT1 (0.41) | JAK2BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6352958-B1 | PRE- AND POST-EMERGENCE HERBICIDES | FMC CORPORATION | 2002-03-05 | — | — | US | disclosed |
| US-6077812-A | 4-OR 7-(2,6-DI(OXO),3-SUBSTITUTED, 4-TRIFLUOROMETHYL-1,2,3, 6-TETRAHYDROPYRIMIDIN-1-YL)BENZIMIDAZOLES; CONTROLLING WEEDS | FMC CORPORATION (US) | 2000-06-20 | — | — | US | disclosed |
| EP-0968207-A1 | CYCLOIMIDO-SUBSTITUTED BENZOFUSED HETEROCYCLIC HERBICIDES | FMC CORPORATION (US) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998038188-A1 | CYCLOIMIDO-SUBSTITUTED BENZOFUSED HETEROCYCLIC HERBICIDES | FMC CORPORATION (US) | 1998-09-03 | — | — | WO | disclosed |
| US-4859229-A | HERBICIDES | HOFFMANN-LA ROCHE INC. (US) | 1989-08-22 | — | — | US | disclosed |
| EP-0255047-A1 | 3-Aryl uraciles and their use as herbicides | CIBA-GEIGY AG (CH) | 1988-02-03 | — | — | EP | disclosed |