Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 4/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | USP7 | Q93009 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743866 | 0.78 | KMT2A (0.59) | LARS1MMP8ALDH1A1ANPEP | |
| SCHEMBL22522245 | 0.78 | KMT2A (0.59) | LARS1MMP8ALDH1A1ANPEP | |
| SCHEMBL1792751 | 0.78 | KMT2A (0.59) | LARS1MMP8ALDH1A1ANPEP | |
| Hydrochloric Acid SCHEMBL10520633 | 0.76 | KMT2A (0.58) | LARS1MMP8ALDH1A1ANPEP | |
| Acetic Acid SCHEMBL11135238 | 0.75 | ALDH1A1 (0.56) | LARS1MMP8ALDH1A1ANPEP | |
| SCHEMBL25747721 | 0.75 | RARG (0.48) | LMNARARGRORCADORA3ALDH1A1 | |
| SCHEMBL25747720 | 0.74 | RARG (0.47) | CYP3A4TSHRHPGDRARGRORC | |
| SCHEMBL25747719 | 0.74 | RARG (0.45) | LMNAHPGDRARGRORCADORA3 | |
| SCHEMBL7371699 | 0.72 | ALDH1A1 (0.52) | LARS1HPGDMMP8ALDH1A1ANPEP | |
| SCHEMBL15623810 | 0.71 | ERAP2 (0.53) | LARS1MMP8ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458781-B1 | BLOCKERS CALCIUM CHANNEL ANTAGONISTS FOR STROKES, BRAIN DISORDERS | WARNER-LAMBERT COMPANY | 2002-10-01 | — | — | US | disclosed |