Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7682080 | 0.82 | LSS (0.54) | LSSKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL7655662 | 0.74 | LSS (0.49) | LSSKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL7655660 | 0.73 | LSS (0.48) | LSSSMN1; SMN2KDM4EALDH1A1MAPT | |
| SCHEMBL9514839 | 0.73 | GBA1 (0.65) | LSSSMN1; SMN2KDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7654158 | 0.73 | HRH4 (0.44) | SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL7654098 | 0.72 | L3MBTL1 (0.45) | SMN1; SMN2KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL3599373 | 0.71 | IKBKB (0.67) | — | |
| SCHEMBL8123271 | 0.70 | IKBKB (0.45) | KDM4EALDH1A1MAPTHSD11B1ABL1 | |
| SCHEMBL6981493 | 0.69 | LSS (0.69) | LSSSMN1; SMN2KDM4EMAPTMEN1 | |
| SCHEMBL3613226 | 0.69 | KDM4E (0.74) | SMN1; SMN2KDM4EALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6335341-B1 | ANTICHOLESTEROL AGENTS; ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 2002-01-01 | — | — | US | disclosed |