Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | USP7 | Q93009 | 2/20 | 0.44 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7662050 | 0.81 | HTR2A (0.47) | L3MBTL1SLC6A7KDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7654158 | 0.76 | HRH4 (0.44) | MEN1KMT2AALDH1A1MAPK1HSD17B10 | |
| SCHEMBL8311501 | 0.75 | LSS (0.55) | L3MBTL1SLC6A7KDM4EMEN1KMT2A | |
| SCHEMBL7655661 | 0.75 | LSS (0.48) | KDM4EKMT2A | |
| SCHEMBL9513674 | 0.74 | KDM4E (0.59) | L3MBTL1SLC6A7KDM4EALDH1A1MAPK1 | |
| SCHEMBL7658281 | 0.72 | LSS (0.47) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL13392116 | 0.70 | GRM5 (0.52) | USP7MEN1KMT2ALMNAMAPT | |
| SCHEMBL6980429 | 0.69 | SLC6A7 (0.56) | L3MBTL1SLC6A7KDM4EALDH1A1MAPK1 | |
| SCHEMBL9514848 | 0.68 | ALDH1A1 (0.64) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8118309 | 0.67 | L3MBTL1 (0.41) | L3MBTL1SLC6A7SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6335341-B1 | ANTICHOLESTEROL AGENTS; ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 2002-01-01 | — | — | US | disclosed |