Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | RXRB | P28702 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 6/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26978653 | 0.89 | ALDH1A1 (0.41) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL30524348 | 0.88 | NPC1 (0.46) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL7067289 | 0.88 | NPC1 (0.46) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL374596 | 0.87 | ALDH1A1 (0.40) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL228138 | 0.84 | ALDH1A1 (0.53) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL29631959 | 0.84 | NPC1 (0.40) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL374595 | 0.84 | NPC1 (0.40) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL6056687 | 0.82 | ALDH1A1 (0.36) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL10728586 | 0.82 | ALDH1A1 (0.36) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL29545640 | 0.82 | RXRA (0.43) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240246-A1 | NON-EXUDING OPTICALLY BRIGHTENED POLYOLEFIN BLENDS | EASTMAN CHEMICAL COMPANY (US) | 2002-09-18 | — | — | EP | claimed |
| WO-2001036533-A1 | NON-EXUDING OPTICALLY BRIGHTENED POLYOLEFIN BLENDS | EASTMAN CHEMICAL COMPANY (US) | 2001-05-25 | — | — | WO | claimed |