Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.42 |
| ▸ | IGF1R | P08069 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | PNP | P00491 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2623142 | 0.76 | HPGD (0.52) | MEN1KMT2APNP | |
| SCHEMBL27763565 | 0.76 | KDM4E (0.43) | KDM4EMEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL27763566 | 0.76 | KDM4E (0.43) | KDM4EMEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL7085340 | 0.75 | ADORA2A (0.47) | KDM4EMEN1MAPTKMT2AMME | |
| SCHEMBL27564857 | 0.75 | ADORA2A (0.47) | KDM4EMEN1MAPTKMT2AMME | |
| SCHEMBL2623146 | 0.75 | ALDH1A1 (0.54) | KDM4EMEN1KMT2ACYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL7088885 | 0.74 | ADORA2A (0.47) | KDM4EMEN1MAPTKMT2AMME | |
| SCHEMBL27763562 | 0.74 | KDM4E (0.42) | KDM4EMEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL1412351 | 0.73 | KDM4E (0.40) | KDM4EMEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL27763561 | 0.72 | CXCR2 (0.40) | KDM4EMEN1MAPTKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495528-B1 | ANTIINFLAMMATORY AGENTS; INHIBITING LEUKOCYTE RECRUITMENT AND ACTIVATION; AGONISTS OF ADENOSINE 2A RECEPTOR | SMITHKLINE BEECHAM CORPORATION | 2002-12-17 | — | — | US | disclosed |