Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | GHSR | Q92847 | 6/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717981 | 1.00 | CTSB (0.47) | CTSBCTSSCTSKPPARGPPARD | |
| SCHEMBL7474508 | 0.90 | CTSB (0.42) | CTSBCTSSCTSKPPARGPPARD | |
| SCHEMBL8362302 | 0.90 | CTSB (0.42) | CTSBCTSSCTSKPPARGPPARD | |
| SCHEMBL1401196 | 0.88 | CTSB (0.49) | CTSBCTSSCTSKPPARGPPARA | |
| SCHEMBL3266674 | 0.88 | CTSB (0.49) | CTSBCTSSCTSKPPARGPPARA | |
| SCHEMBL31407327 | 0.88 | CTSB (0.49) | CTSBCTSSCTSKPPARGPPARA | |
| SCHEMBL29624575 | 0.88 | CTSB (0.49) | CTSBCTSSCTSKPPARGPPARA | |
| SCHEMBL7286769 | 0.88 | CTSB (0.49) | CTSBCTSSCTSKPPARGPPARA | |
| SCHEMBL12600955 | 0.85 | ITGA4 (0.49) | CTSBCTSSCTSKMMP13ACE | |
| SCHEMBL8724329 | 0.85 | ITGA4 (0.49) | CTSBCTSSCTSKMMP13ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350767-B1 | GROWTH HORMONE RELEASE STIMULANT | NOVO NORDISK A/S (DK) | 2002-02-26 | — | — | US | disclosed |
| EP-0833845-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1998-04-08 | — | — | EP | disclosed |
| WO-1997000894-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-01-09 | — | — | WO | disclosed |