Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | GHSR | Q92847 | 3/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 3/20 | 0.43 |
| ▸ | ACE | P12821 | 3/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1401196 | 1.00 | CTSB (0.49) | CTSBCTSSCTSKGHSRPTPN1 | |
| SCHEMBL31407327 | 1.00 | CTSB (0.49) | CTSBCTSSCTSKGHSRPTPN1 | |
| SCHEMBL7286769 | 1.00 | CTSB (0.49) | CTSBCTSSCTSKGHSRPTPN1 | |
| SCHEMBL3266674 | 1.00 | CTSB (0.49) | CTSBCTSSCTSKGHSRPTPN1 | |
| SCHEMBL8299432 | 0.89 | CTSB (0.43) | CTSBCTSSCTSKGHSRPTPN1 | |
| SCHEMBL8717981 | 0.88 | CTSB (0.47) | CTSBCTSSCTSKGHSRPTPN1 | |
| SCHEMBL7658636 | 0.88 | CTSB (0.47) | CTSBCTSSCTSKGHSRPTPN1 | |
| SCHEMBL6317705 | 0.87 | GHSR (0.48) | CTSBCTSSCTSKGHSRPTPN1 | |
| SCHEMBL2476924 | 0.86 | MMP13 (0.46) | CTSBCTSSCTSKACEMMP13 | |
| SCHEMBL1401042 | 0.86 | MMP13 (0.46) | CTSBCTSSCTSKACEMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112300247-B | Teixobactin analogue and application thereof | 广东东阳光药业有限公司 | 2022-12-27 | — | — | CN | disclosed |
| EP-4004015-A1 | A TEIXOBACTIN ANALOGUE AND USE THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2022-06-01 | — | — | EP | disclosed |