SCHEMBL7659016

SCHEMBL7659016

O=C(O)C(Br)CC(CCCBr)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
TSHR P16473 1/20 0.44
SLC1A2 P43004 3/20 0.40
SLC1A1 P43005 3/20 0.40
SLC1A3 P43003 2/20 0.40
LCK P06239 1/20 0.39
PPARD Q03181 1/20 0.39
ZDHHC20 Q5W0Z9 1/20 0.39
ZDHHC2 Q9UIJ5 1/20 0.39
GRIK1 P39086 4/20 0.39
GRIK2 Q13002 3/20 0.39
CA2 P00918 1/20 0.38
MAPK1 P28482 1/20 0.38
CPB2 Q96IY4 1/20 0.35
FOLH1 Q04609 1/20 0.34
GRM2 Q14416 1/20 0.34
GRM3 Q14832 1/20 0.34
CHRM1 P11229 1/20 0.33
AKR1A1 P14550 1/20 0.33
CHRM3 P20309 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3875750 0.80
SCHEMBL7971596 0.80
SCHEMBL4410902 0.78 CHRM1 (0.44) SLC1A2SLC1A1SLC1A3GRIK1GRIK2
SCHEMBL11633541 0.78 CA2 (0.43) ALDH1A1TSHRSLC1A2SLC1A1SLC1A3
Hydrochloric Acid SCHEMBL5555196 0.78 LCK (0.56) ALDH1A1TSHRLCKPPARDZDHHC20
SCHEMBL1554383 0.74 CA2 (0.68) SLC1A2SLC1A1SLC1A3LCKPPARD
SCHEMBL4414310 0.73 LCK (0.61) ALDH1A1TSHRLCKPPARDZDHHC20
SCHEMBL7971309 0.73 LCK (0.61) ALDH1A1TSHRLCKPPARDZDHHC20
SCHEMBL15032840 0.72 ALDH1A1 (0.41) ALDH1A1TSHRSLC1A2SLC1A1SLC1A3
SCHEMBL10412071 0.72 CHRM1 (0.70) TSHRSLC1A2SLC1A1SLC1A3LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6376510-B1 ADMINISTERING A ALKOXY- AND ACYLOXY-SUBSTITUTED ARALKYL AND ARALKENYL BIS QUATERNARY AMMONIUM DERIVATIVES OF CYCLIC ALKANOL DIESTERS TO A HUMAN AS MUSCLE RELAXANTS NEWLAXANT LLC 2002-04-23 US disclosed