Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10815559 | 0.76 | KMT2A (0.75) | KMT2AMEN1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7665105 | 0.75 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10USP2LMNA | |
| SCHEMBL7659412 | 0.72 | ADORA2B (0.45) | KMT2AMEN1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7670431 | 0.70 | ADORA2B (0.54) | KMT2AMEN1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7666660 | 0.70 | ADORA2B (0.54) | KMT2APOLBADORA2B | |
| SCHEMBL555093 | 0.69 | ALDH1A1 (0.65) | KMT2AMEN1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8560750 | 0.69 | PDE4A (0.52) | HSD17B10ADORA2B | |
| SCHEMBL8559651 | 0.69 | ADORA2B (0.61) | KMT2AMEN1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7668670 | 0.68 | ADORA2B (0.51) | KMT2AMEN1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8562832 | 0.68 | ADORA2B (0.43) | ALDH1A1KDM4EHSD17B10TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492377-B1 | Imidazotriazolopyrimidines with adenosine-antagonistic activity | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |