Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 7/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.49 |
| ▸ | F10 | P00742 | 11/20 | 0.48 |
| ▸ | F2 | P00734 | 4/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7667899 | 0.90 | LOXL2 (0.56) | PRSS1F10F2LOXL2PLG | |
| SCHEMBL7662102 | 0.89 | F10 (0.46) | PRSS1F10F2LOXL2PLG | |
| SCHEMBL7662094 | 0.88 | F10 (0.46) | PRSS1PRSS2PRSS3F10F2 | |
| SCHEMBL7664103 | 0.88 | F10 (0.62) | PRSS1PRSS2PRSS3F10F2 | |
| SCHEMBL7719048 | 0.84 | F2 (0.66) | PRSS1F10F2 | |
| SCHEMBL7314024 | 0.83 | F10 (0.54) | PRSS1PRSS2PRSS3F10F2 | |
| SCHEMBL7664269 | 0.82 | F2 (0.60) | PRSS1F10F2LOXL2 | |
| SCHEMBL7666941 | 0.82 | F2 (0.60) | PRSS1PRSS2PRSS3F10F2 | |
| SCHEMBL7663246 | 0.81 | MRGPRX4 (0.48) | LOXL2LMNAHPGD | |
| SCHEMBL7063308 | 0.81 | CHRM3 (0.40) | PRSS1F10F2LOXL2PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348478-B1 | BLOOD COAGULATION FACTORS AND ANTICOAGULANTS | TEIJIN LIMITED (JP) | 2002-02-19 | — | — | US | disclosed |
| EP-1043311-A1 | BIPHENYLAMIDINE DERIVATIVES | TEIJIN LIMITED (JP) | 2000-10-11 | — | — | EP | disclosed |