Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 1.00 |
| ▸ | HCRTR2 | O43614 | 3/20 | 1.00 |
| ▸ | HTR2B | P41595 | 3/20 | 0.57 |
| ▸ | HTR2C | P28335 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | GSK3A | P49840 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38660785 | 1.00 | HCRTR1 (1.00) | HCRTR1HCRTR2HTR2BHTR2CMAPT | |
| Hydrochloric Acid SCHEMBL7655748 | 0.82 | HCRTR1 (0.70) | HCRTR1HCRTR2HTR2BHTR2CMAPT | |
| SCHEMBL7101667 | 0.77 | HTR2C (0.72) | HCRTR1HCRTR2HTR2BHTR2CMAPT | |
| Hydrochloric Acid SCHEMBL5964738 | 0.76 | HTR2C (0.70) | HCRTR1HCRTR2HTR2BHTR2CMAPT | |
| Hydrochloric Acid SCHEMBL7654789 | 0.74 | HTR2B (0.71) | HCRTR1HCRTR2HTR2BHTR2CMAPT | |
| SCHEMBL7659058 | 0.74 | HTR2B (0.64) | HCRTR1HCRTR2HTR2BHTR2CMAPT | |
| SCHEMBL29663991 | 0.73 | RAB9A (0.76) | HTR2BHTR2CMAPTMEN1KMT2A | |
| SCHEMBL7656800 | 0.73 | HTR2B (0.66) | HCRTR1HCRTR2HTR2BHTR2CMAPT | |
| Hydrochloric Acid SCHEMBL7658449 | 0.73 | HTR2B (0.66) | HCRTR1HCRTR2HTR2BHTR2CMAPT | |
| Hydrochloric Acid SCHEMBL7663226 | 0.73 | HTR2B (0.69) | HCRTR1HCRTR2HTR2BHTR2CMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8568997-B2 | Detection system and uses therefor | DIMERIX BIOSCIENCE PTY LTD. (AU) | 2013-10-29 | — | — | US | disclosed |
| EP-2605015-A1 | Kits for determining the interaction of a test compound with two associated receptors | Dimerix Bioscience Pty.Ltd. (AU) | 2013-06-19 | — | — | EP | disclosed |
| EP-2080012-B1 | Methods for assaying test compounds on associated receptors | DIMERIX BIOSCIENCE PTY LTD (AU) | 2013-03-20 | — | — | EP | disclosed |
| US-20130065253-A1 | DETECTION SYSTEM AND USES THEREFOR | DIMERIX BIOSCIENCE PTY LTD. (AU) | 2013-03-14 | — | — | US | disclosed |
| US-8283127-B2 | Detection system and uses therefor | DIMERIX BIOSCIENCE PTY LTD. (AU) | 2012-10-09 | — | — | US | disclosed |
| US-20100234417-A1 | THYROTROPIN RELEASING HORMONE RECEPTOR-OREXIN RECEPTOR HETERO-DIMERS/-OLIGOMERS | DIMERIX BIOSCIENCE PTY LTD. (AU) | 2010-09-16 | — | — | US | disclosed |
| WO-2010031114-A1 | NOVEL RECEPTOR HETERO-DIMERS/-OLIGOMERS | DIMERIX BIOSCIENCE PTY LTD (AU) | 2010-03-25 | — | — | WO | disclosed |
| US-20100021457-A1 | DETECTION SYSTEM AND USES THEREFOR | DIMERIX BIOSCIENCE PTY LTD. (AU) | 2010-01-28 | — | — | US | disclosed |
| EP-2080012-A1 | DETECTION SYSTEM AND USES THEREFOR | Dimerix Bioscience Pty.Ltd. (AU) | 2009-07-22 | — | — | EP | disclosed |
| EP-2078037-A1 | THYROTROPIN RELEASING HORMONE RECEPTOR-OREXIN RECEPTOR HETERO-DIMERS/-OLIGOMERS | Dimerix Bioscience Pty.Ltd. (AU) | 2009-07-15 | — | — | EP | disclosed |
| WO-2008055314-A1 | THYROTROPIN RELEASING HORMONE RECEPTOR-OREXIN RECEPTOR HETERO-DIMERS/-OLIGOMERS | DIMERIX BIOSCIENCE PTY LTD (AU) | 2008-05-15 | — | — | WO | disclosed |
| WO-2008055313-A1 | DETECTION SYSTEM AND USES THEREFOR | DIMERIX BIOSCIENCE PTY LTD (AU) | 2008-05-15 | — | — | WO | disclosed |