SCHEMBL7659271

SCHEMBL7659271

CC(C)(C)OC(CN)(N=C=O)C(=O)O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28858704 0.85
SCHEMBL29257230 0.84 ODC1 (0.30)
SCHEMBL17416332 0.82
SCHEMBL346194 0.81
SCHEMBL5843646 0.80 ALDH1A1 (0.30)
SCHEMBL14638339 0.76
SCHEMBL7826229 0.74 BLM (0.48) KDM4E
SCHEMBL3439004 0.74 BLM (0.48) KDM4E
SCHEMBL15467506 0.73 CTSS (0.38)
SCHEMBL5352693 0.72 ALDH1A1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6344452-B1 GASTRIN RECEPTOR ANTAGONIST, GASTROINTESTINAL DISORDERS, ETC ZERIA PHARMACEUTICALS CO., LTD. (JP) 2002-02-05 US disclosed
EP-1085014-A1 1,5-BENZODIAZEPINE DERIVATIVES Zeria Pharmaceutical Co., Ltd. (JP) 2001-03-21 EP disclosed