Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 7/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3439004 | 1.00 | BLM (0.48) | BLMESR1ESR2CTSSCTSK | |
| SCHEMBL15467506 | 0.88 | CTSS (0.38) | BLMCTSSCTSKTSHRRECQL | |
| SCHEMBL1310582 | 0.86 | LDHA (0.40) | KMT2AALDH1A1POLBCTBP2PPARA | |
| SCHEMBL28247561 | 0.86 | LDHA (0.40) | KMT2AALDH1A1POLBCTBP2PPARA | |
| SCHEMBL4112961 | 0.76 | NPSR1 (0.49) | BLMMEN1KMT2ATSHRHSD17B10 | |
| SCHEMBL7659271 | 0.74 | KDM4E (0.31) | KDM4E | |
| SCHEMBL28858704 | 0.74 | — | — | |
| SCHEMBL206553 | 0.74 | SMN1; SMN2 (0.42) | TSHRALDH1A1CYP3A4CYP1A2RECQL | |
| SCHEMBL28129053 | 0.72 | ESR1 (0.37) | BLMESR1ESR2CTSSCTSK | |
| SCHEMBL7818498 | 0.71 | SMN1; SMN2 (0.40) | HSD17B10ALDH1A1POLBRECQLPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |