Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7657921 | 0.89 | PARP1 (0.47) | ALDH1A1KDM4EHPGDCTNNB1PKM | |
| SCHEMBL7655361 | 0.87 | KDM4E (0.48) | ALDH1A1KDM4EHPGDALOX5TP53 | |
| SCHEMBL2957205 | 0.87 | CTNNB1 (0.46) | ALDH1A1KDM4EHPGDCTNNB1PKM | |
| Ammonia Solution, Strong SCHEMBL6532360 | 0.86 | CTNNB1 (0.46) | ALDH1A1KDM4EHPGDCTNNB1PKM | |
| SCHEMBL2955515 | 0.83 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDCTNNB1PKM | |
| SCHEMBL2955144 | 0.83 | ALOX5 (0.51) | ALDH1A1KDM4EHPGDCTNNB1PKM | |
| SCHEMBL2955149 | 0.83 | ALOX5 (0.51) | ALDH1A1KDM4EHPGDCTNNB1PKM | |
| SCHEMBL2952044 | 0.81 | PARP1 (0.46) | ALDH1A1KDM4EHPGDCTNNB1PKM | |
| SCHEMBL2955345 | 0.81 | KDM4E (0.43) | ALDH1A1KDM4EHPGDALOX5TP53 | |
| SCHEMBL2954675 | 0.81 | FABP3 (0.40) | ALDH1A1KDM4EHPGDCTNNB1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340704-B1 | TREATING NERVE DISEASE OR BONE/JOINT DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0975621-A1 | CELL DIFFERENTIATION INDUCING AMIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998049155-A1 | CELL DIFFERENTIATION INDUCING AMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-05 | — | — | WO | disclosed |