Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6191271 | 0.81 | NPC1 (0.45) | CASP3NPC1RAB9ASMN1; SMN2RECQL | |
| SCHEMBL6187342 | 0.75 | NPC1 (0.52) | CASP3NPC1RAB9ASMN1; SMN2MGLL | |
| SCHEMBL4028517 | 0.74 | CASP3 (0.47) | CASP3NPC1RAB9ASMN1; SMN2MGLL | |
| SCHEMBL2290346 | 0.73 | TRPM8 (0.55) | NPC1 | |
| SCHEMBL3255272 | 0.72 | KCNA5 (0.54) | SMN1; SMN2LMNA | |
| SCHEMBL6189531 | 0.71 | TACR3 (0.53) | CASP3NPC1RAB9AMGLLL3MBTL1 | |
| SCHEMBL17140939 | 0.71 | POLB (0.50) | NPC1RAB9ASMN1; SMN2MGLLALDH1A1 | |
| SCHEMBL13666704 | 0.71 | POLB (0.56) | NPC1RAB9ASMN1; SMN2MGLLALDH1A1 | |
| SCHEMBL18702922 | 0.71 | SCN9A (0.53) | NPC1RAB9ASCN9AL3MBTL1 | |
| SCHEMBL6779096 | 0.70 | ALDH1A1 (0.54) | SMN1; SMN2L3MBTL1ALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6352982-B1 | TREATING DIABETES, OBESITY, OR INVETERATE DIARRHEA IN A MAMMAL WHICH COMPRISES ADMINISTERING AN EFFECTIVE AMOUNT OF A COMPOUND OF | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-03-05 | — | — | US | disclosed |