Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7659907 | 1.00 | ALDH1A1 (0.45) | ALDH1A1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL11585384 | 0.87 | PKM (0.42) | ALDH1A1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL77023 | 0.87 | NOTUM (0.44) | ALDH1A1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL77024 | 0.87 | NOTUM (0.44) | ALDH1A1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL10681617 | 0.84 | ALDH1A1 (0.46) | ALDH1A1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL8408150 | 0.83 | ALDH1A1 (0.40) | ALDH1A1MAPTKMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL11587023 | 0.83 | NOTUM (0.35) | ALDH1A1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL7095410 | 0.80 | NOTUM (0.44) | ALDH1A1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL9419477 | 0.77 | CYP1A2 (0.42) | ALDH1A1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL9419480 | 0.77 | CYP1A2 (0.42) | ALDH1A1MAPTKMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6489374-B1 | ORGANONITROGEN COMPOUNDS THAT YIELD AMINES, IMINES OR AMIDINES WHEN EXPOSED TO VISIBLE OR ULTRAVIOLET RADIATION; POLYMERIZATION CATALYSTS USED IN ONE-POT SYSTEMS HAVING STORAGE STABILITY | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-12-03 | — | — | US | disclosed |
| US-4123418-A | BIS-(U8I8I8L8L-PENTAMETHY TETRAMETHYL-4-PIPERIDYL)-SUBERATE | CIBA-GEIGY CORPORATION (US) | 1978-10-31 | — | — | US | disclosed |
| US-4110304-A | STERICALLY HINDERED CYCLIC AMINE | CIBA-GEIGY CORPORATION (US) | 1978-08-29 | — | — | US | disclosed |
| US-4061631-A | STABILIZER | CIBA-GEIGY CORPORATION (US) | 1977-12-06 | — | — | US | disclosed |