SCHEMBL766046

SCHEMBL766046

O=C(/C=C/c1cc(Cl)ccc1O)N1CCCCC1

nearest known ligand 0.64

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PELI1 Q96FA3 3/20 0.64
ALDH1A1 P00352 4/20 0.55
RAB9A P51151 4/20 0.55
MAPT P10636 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
ALOX5 P09917 2/20 0.52
MAOB P27338 1/20 0.52
TRPV1 Q8NER1 2/20 0.52
HPGD P15428 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
GAA P10253 2/20 0.46
ERN1 O75460 1/20 0.46
NPC1 O15118 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10445978 0.85 PELI1 (0.67) PELI1ALDH1A1RAB9AMAPTL3MBTL1
SCHEMBL10446033 0.83 PELI1 (0.63) PELI1ALDH1A1RAB9AMAPTL3MBTL1
SCHEMBL766012 0.83 PELI1 (0.64) PELI1ALDH1A1RAB9AMAPTL3MBTL1
SCHEMBL10445937 0.82 PELI1 (0.63) PELI1ALDH1A1RAB9AMAPTL3MBTL1
SCHEMBL10446313 0.82 PELI1 (0.67) PELI1ALDH1A1RAB9AMAPTL3MBTL1
SCHEMBL10446416 0.82 PELI1 (0.63) PELI1ALDH1A1RAB9AMAPTL3MBTL1
SCHEMBL10445972 0.82 PELI1 (0.67) PELI1ALDH1A1RAB9AMAPTL3MBTL1
SCHEMBL10446290 0.82 PELI1 (0.62) PELI1ALDH1A1RAB9AMAPTL3MBTL1
SCHEMBL6094563 0.81 PELI1 (0.62) PELI1ALDH1A1RAB9AMAPTL3MBTL1
SCHEMBL13087237 0.80 PELI1 (0.60) PELI1ALDH1A1RAB9AMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120070781-A1 BASE GENERATOR, PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING MATERIAL COMPRISING THE PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING METHOD USING THE PHOTOSENSITIVE RESIN COMPOSITION AND PRODUCTS COMPRISING THE SAME DAI NIPPON PRINTING CO., LTD. (JP) 2012-03-22 US disclosed
US-20120070781-A1 BASE GENERATOR, PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING MATERIAL COMPRISING THE PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING METHOD USING THE PHOTOSENSITIVE RESIN COMPOSITION AND PRODUCTS COMPRISING THE SAME DAI NIPPON PRINTING CO., LTD. (JP) 2012-03-22 US disclosed
WO-2010113813-A1 BASE-GENERATING AGENT, PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING MATERIAL COMPRISING THE PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING METHOD AND ARTICLE USING THE PHOTOSENSITIVE RESIN COMPOSITION 大日本印刷株式会社 (JP) 2010-10-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120070781-A1 BASE GENERATOR, PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING MATERIAL COMPRISING THE PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING METHOD USING THE PHOTOSENSITIVE RESIN COMPOSITION AND PRODUCTS COMPRISING THE SAME RER1, SUN2, REV1 PELI1 585/4885ALDH1A1 2053/4885RAB9A 1268/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.