Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | DRD4 | P21917 | 3/20 | 0.34 |
| ▸ | DRD3 | P35462 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | OXTR | P30559 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7660831 | 1.00 | LMNA (0.35) | LMNAHTTDRD2DRD4DRD3 | |
| SCHEMBL7665426 | 1.00 | LMNA (0.35) | LMNAHTTDRD2DRD4DRD3 | |
| SCHEMBL7673478 | 0.99 | LMNA (0.35) | LMNAHTTDRD2DRD4DRD3 | |
| SCHEMBL7840098 | 0.96 | LMNA (0.36) | LMNAHTTDRD2DRD4DRD3 | |
| SCHEMBL7671762 | 0.93 | DRD2 (0.34) | LMNAHTTDRD2DRD4DRD3 | |
| SCHEMBL7672200 | 0.92 | DRD2 (0.36) | LMNAHTTDRD2DRD4DRD3 | |
| SCHEMBL7673978 | 0.88 | LMNA (0.39) | LMNAHTTDRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL7673969 | 0.87 | LMNA (0.39) | LMNAHTTDRD2DRD4DRD3 | |
| SCHEMBL7663037 | 0.85 | DRD2 (0.37) | LMNAHTTDRD2DRD4DRD3 | |
| SCHEMBL7667788 | 0.84 | LMNA (0.41) | LMNAHTTDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403607-B1 | ANTIULCER | Hidaka, Hiroyoshi (JP) | 2002-06-11 | — | — | US | disclosed |
| EP-1072587-A1 | SULFONAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | Hidaka, Hiroyoshi (JP) | 2001-01-31 | — | — | EP | disclosed |