Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 3/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7673969 | 0.99 | LMNA (0.39) | LMNAHTTTHRATHRBHRH3 | |
| SCHEMBL7667788 | 0.96 | LMNA (0.41) | LMNAHTTHRH3DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL7667777 | 0.95 | LMNA (0.40) | LMNAHTTHRH3DRD2DRD4 | |
| SCHEMBL7672852 | 0.91 | HRH3 (0.41) | LMNAHTTHRH3DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL7672849 | 0.90 | BLM (0.41) | LMNAHTTHRH3DRD2DRD4 | |
| SCHEMBL7660831 | 0.88 | LMNA (0.35) | LMNAHTTDRD2DRD4DRD3 | |
| SCHEMBL7660725 | 0.88 | LMNA (0.35) | LMNAHTTDRD2DRD4DRD3 | |
| SCHEMBL7665426 | 0.88 | LMNA (0.35) | LMNAHTTDRD2DRD4DRD3 | |
| SCHEMBL7673478 | 0.86 | LMNA (0.35) | LMNAHTTDRD2DRD4DRD3 | |
| SCHEMBL7840098 | 0.84 | LMNA (0.36) | LMNAHTTDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403607-B1 | ANTIULCER | Hidaka, Hiroyoshi (JP) | 2002-06-11 | — | — | US | disclosed |